Heteromultimeric P2X1/2 Receptors Show a Novel Sensitivity to Extracellular pH
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چکیده
منابع مشابه
Heteromultimeric P2X(1/2) receptors show a novel sensitivity to extracellular pH.
Rat P2X(1) and P2X(2) subunits were coexpressed in defolliculated Xenopus oocytes and the resultant P2X receptors studied under voltage-clamp conditions. Extracellular ATP elicited biphasic inward currents, involving an initial rapidly inactivating (P2X(1)-like) component and a later slowly inactivating (P2X(2)-like) component. The maximum amplitude of P2X(1)-like ATP responses was increased in...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Experimental Therapeutics
سال: 2002
ISSN: 0022-3565,1521-0103
DOI: 10.1124/jpet.300.2.673